The Whites stand an excellent chance of securing a top-half finish in their first Premier League campaign in 16 years, and could even secure Europa League qualification should they maintain their fine run of form over the course of their remaining six matches of the season.
Speaking ahead of the big game, Red Devils midfielder Fred hyped up the rivalry between the two teams and the significance of the fixture, and contended: “It's an English football Clasico. We get a feel for this anticipation from social media. The fans are excited about this game, as are we of course.
“We haven't had a midweek game this week, so the anticipation for the next game increases and it's a derby game against a massive rival. “It'll be a really tough game but we'll be preparing well for it this week.”
He continued: “I don't know if it was our best performance of the season (their last match league game against Leeds), (but) 6-2 was a great result of course.
“I think we've had better performances this season... we're prepared for this, we know how they play and we'll aim to be at our very best to get the win.”Here are today's biggest transfer stories and the latest team news involving Leeds United and the rest of the Premier League, as the build-up to the weekend action continues:
1. Fernandes' future depends on Pogba
Manchester United talisman Bruno Fernandes has been tipped to sign a new £200k-per-week contract - doubling his existing salary - with the club, but will only do so if France international Paul Pogba also remains at Old Trafford. (Daily Mail) Photo: OLI SCARFF
2. Seagulls among favourites to sign WBA star
Brighton & Hove Albion have been named among the favourites to sign West Brom's star goalkeeper Sam Johnston this summer. However, the likes of West Ham and Man Utd look to have a significantly better chance of signing the England hopeful. (SkyBet) Photo: RUI VIEIRA
3. Man Utd turn attention to Varane
Following news of Real Madrid snapping up Bayern Munich defender David Alaba, Manchester United have been tipped to swoop for Los Blancos ace Raphael Varane this summer. However, they could face competition from Chelsea. (Manchester Evening News) Photo: Denis Doyle
4. West Ham could spend big on striker
Reports from Spain have claimed that West Ham United are willing to spend an eye-watering £40m on Sevilla striker Youssef En-Nesyri this summer. The 23-year-old, who is also on Juventus' radar, has scored 17 goals in La Liga so far this season. (Sport Witness) Photo: Lars Baron
5. Pundit makes bold Bielsa suggestion
Pundit Jamie O'Hara has controversially claimed that ex-European Super League side Spurs are a "bigger club" than Leeds United, and urged Whites boss Marcelo Bielsa to take the vacant role of Tottenham manager following Jose Mourinho's exit. (talkSPORT) Photo: IAN WALTON
6. Perez fires ESL warning shot
Real Madrid president Florentino Perez has insisted that the European Super League is still "on standby" despite nine of the twelve founding teams, including all six from England, announcing their withdrawal following a mass public outcry. (BBC Sport) Photo: Eric Alonso